The GnomeDX and GnomeSciences Variant Detection Service will detect SARS-CoV-2 mutations in virus variants classified as Variants of Concern (VOC).
Variants of Concern have been shown to have an increase in transmissibility, more severe disease, significant reduction in neutralization by antibodies generated during previous infection or vaccination, and reduced effectiveness of treatments or vaccines, or diagnostic detection failures. This includes the UK (B.1.1.7), South Africa (B.1.351), Brazil (P.1), and California (B.1.427) variants.
The Variant Detection Service is research use only.
Contact us to speak with our scientists about research capabilities.
Viruses are constantly evolving, and GnomeDX and GnomeSciences have developed a solution to efficiently investigate variants with mutations in the Spike protein of SARS-CoV-2. The detection of variants will help public health efforts and may contribute to research regarding transmissibility, treatment, vaccination and testing strategy.
The GnomeDX Variant Detection Service combines real-time reverse transcription polymerase chain reaction (RT-PCR) and direct sequencing of the SARS CoV-2 spike protein to differentiate the mutations for these variants. Sequencing is performed on the Spike protein gene, including the N-Terminal Domain (NTD) and Receptor Binding Domain (RBD) of the Spike protein, where most Spike protein mutations have been found to occur.