Peer Reviewed Publications by the Gnome Team

Estfanous S, Daily KP, Eltobgy M, Deems NP, Anne MNK, Krause K, Badr A, Hamilton K, Mikhail A, Nuovo G, Barrientos RM, Gavrilin MA, Amer AO
Elevated Expression of MiR-17 in Microglia of Alzheimer’s Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation.

Front Immunol (2021 Jul 27) 12:705581. doi: 10.3389/fimmu.2021.705581. eCollection 2021.PMID: 34426734 Free PMC

Nuovo G, Amann V, Williams J, Vandiver P, Quinonez M, Fadda P, Paniccia B, Mezache L, Mikhail A.
Increased expression of importin-β, exportin-5 and nuclear transportable proteins in Alzheimer’s disease aids anatomic pathologists in its diagnosis.

Ann Diagn Pathol (2018 Feb) 32:10-16. doi: 10.1016/j.anndiagpath.2017.08.003. Epub 2017 Sep 7.PMID: 29414391

Nuovo G, Paniccia B, Mezache L, Quiñónez M, Williams J, Vandiver P, Fadda P, Amann V
Diagnostic pathology of Alzheimer’s disease from routine microscopy to immunohistochemistry and experimental correlations.

Ann Diagn Pathol (2017 Jun) 28:24-29. doi: 10.1016/j.anndiagpath.2017.02.006. Epub 2017 Feb 13.PMID: 28648936

Mezache L, Mikhail M, Garofalo M, Nuovo GJ
Reduced miR-512 and the Elevated Expression of Its Targets cFLIP and MCL1 Localize to Neurons With Hyperphosphorylated Tau Protein in Alzheimer Disease.

Appl Immunohistochem Mol Morphol (2015 Oct) 23(9):615-23. doi: 10.1097/PAI.0000000000000147.PMID: 26258756

Tili E, Mezache L, Michaille JJ, Amann V, Williams J, Vandiver P, Quinonez M, Fadda P, Mikhail A, Nuovo G
microRNA 155 up regulation in the CNS is strongly correlated to Down’s syndrome dementia.

Ann Diagn Pathol (2018 Jun) 34:103-109. doi: 10.1016/j.anndiagpath.2018.03.006. Epub 2018 Mar 26.PMID: 29661714

Awad H, Tili E, Nuovo G, Kelani H, Ramadan ME, Williams J, Binzel K, Rajan J, Mast D, Efanov AA, Rasul KB, Moore S, Basso M, Mikhail A, El-Sayed H
Endovascular repair and open repair surgery of thoraco-abdominal aortic aneurysms cause drastically different types of spinal cord injury.

Sci Rep (2021 Apr 9) 11(1):7834. doi: 10.1038/s41598-021-87324-6.PMID: 33837260 Free PMC article.

Magro CM, Mulvey J, Kubiak J, Mikhail S, Suster D, Crowson AN, Laurence J, Nuovo G
Severe COVID-19: A multifaceted viral vasculopathy syndrome.

Ann Diagn Pathol (2021 Feb) 50:151645. doi: 10.1016/j.anndiagpath.2020.151645. Epub 2020 Oct 13.PMID: 33248385 Free PMC article.

Nuovo GJ, Magro C, Shaffer T, Awad H, Suster D, Mikhail S, He B, Michaille JJ, Liechty B, Tili E
Endothelial cell damage is the central part of COVID-19 and a mouse model induced by injection of the S1 subunit of the spike protein.

Ann Diagn Pathol (2021 Apr) 51:151682. doi: 10.1016/j.anndiagpath.2020.151682. Epub 2020 Dec 24.PMID: 33360731 Free PMC article.

Nuovo GJ, Magro C, Mikhail A
Cytologic and molecular correlates of SARS-CoV-2 infection of the nasopharynx.

Ann Diagn Pathol (2020 Oct) 48:151565

Mulvey JJ, Magro CM, Ma LX, Nuovo GJ, Baergen RN
Analysis of complement deposition and viral RNA in placentas of COVID-19 patients.

Ann Diagn Pathol (2020 Jun) 46:151530

Magro CM, Mulvey JJ, Laurence J, Sanders S, Crowson AN, Grossman M, Harp J, Nuovo G
The differing pathophysiologies that underlie COVID-19-associated perniosis and thrombotic retiform purpura: a case series.

Br J Dermatol (2021 01) 184(1):141-150

Magro CM, Mulvey JJ, Laurence J, Seshan S, Crowson AN, Dannenberg AJ, Salvatore S, Harp J, Nuovo GJ
Docked severe acute respiratory syndrome coronavirus 2 proteins within the cutaneous and subcutaneous microvasculature and their role in the pathogenesis of severe coronavirus disease 2019.

Hum Pathol (2020 12) 106:106-116

Showers CR, Nuovo GJ, Lakhanpal A, Siegel CH, Aizer J, Elreda L, Halevi A, Lai AR, Erkan D, Magro CM
A Covid-19 Patient with Complement-Mediated Coagulopathy and Severe Thrombosis.

Pathobiology (2021) 88(1):28-36

Plotz B, Castillo R, Melamed J, Nuovo G, Magro C, Rosenthal P, Belmont HM
Corrigendum to: Focal small bowel thrombotic microvascular injury in COVID-19 mediated by the lectin complement pathway masquerading as lupus enteritis.

Rheumatology (Oxford) (2021 Jun 07)

Rotman JA, Dean KE, Magro C, Nuovo G, Bartolotta RJ
Concomitant calciphylaxis and COVID-19 associated thrombotic retiform purpura.

Skeletal Radiol (2020 Nov) 49(11):1879-1884.

Magro C, Mulvey JJ, Berlin D, Nuovo G, Salvatore S, Harp J, Baxter-Stoltzfus A, Laurence J.
Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases.

Transl Res (2020 06) 220:1-13.